PLEKHS1 and PDCD10

Data Source:
BioGRID (two hybrid)

		PLEKHS1	PDCD10
Description		pleckstrin homology domain containing S1	programmed cell death 10
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process		Angiogenesis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Regulation Of Golgi Organization Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases			Cerebral cavernous malformation
GWAS			Fast beta electroencephalogram ( 28070124) Platelet count ( 32888494)
Interacting Genes		2 interacting genes: PDCD10 TCP11L1	12 interacting genes: C4orf19 CHMP5 FAM118B FARSA FRYL MINAR1 PLEKHS1 PROSER2 STK24 STK25 STK26 STRN
Entrez ID		79949	11235
HPRD ID		12591	10141
Ensembl ID		ENSG00000148735	ENSG00000114209
Uniprot IDs		A0A384P5Z2 Q5SXH7	C9J363 Q9BUL8
PDB IDs			3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ
Enriched GO Terms of Interacting Partners?
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