PDCD10 and STK25

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDCD10	STK25
Description		programmed cell death 10	serine/threonine kinase 25
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex	Golgi Membrane Cytoplasm Golgi Apparatus Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding	Protein Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Angiogenesis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Regulation Of Golgi Organization Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor	Protein Phosphorylation Response To Oxidative Stress Establishment Or Maintenance Of Cell Polarity Signal Transduction Positive Regulation Of Stress-activated MAPK Cascade Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Protein Autophosphorylation Positive Regulation Of Axonogenesis Golgi Localization Establishment Of Golgi Localization Golgi Reassembly
Pathways
Drugs
Diseases		Cerebral cavernous malformation
GWAS		Fast beta electroencephalogram ( 28070124) Platelet count ( 32888494)	Medication use (thyroid preparations) ( 31015401) Prostate cancer ( 23535732) Vitiligo ( 27723757)
Interacting Genes		12 interacting genes: C4orf19 CHMP5 FAM118B FARSA FRYL MINAR1 PLEKHS1 PROSER2 STK24 STK25 STK26 STRN	16 interacting genes: APP CCNDBP1 CEP70 GOLGA2 GOLGA6L9 IHO1 IKBKG LRRK2 MFHAS1 MTDH NEDD4 PDCD10 TRIM27 UBE2D3 YWHAZ ZDHHC17
Entrez ID		11235	10494
HPRD ID		10141	03770
Ensembl ID		ENSG00000114209	ENSG00000115694
Uniprot IDs		C9J363 Q9BUL8	A0A024R4B2 A0A0S2Z4Y2 B3KRS6 B4DMA5 B4DVS7 B4E185 O00506 Q96BA2
PDB IDs		3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ	2XIK 3W8H 4NZW
Enriched GO Terms of Interacting Partners?
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