DHDDS and MT-ND1

Data Source:
HPRD (two hybrid)

		DHDDS	MT-ND1
Description		dehydrodolichyl diphosphate synthase subunit	NADH dehydrogenase subunit 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Dehydrodolichyl Diphosphate Synthase Complex	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane Dendrite Mitochondrial Membrane Neuronal Cell Body
	Molecular Function	Polyprenyltransferase Activity Protein Binding Dehydrodolichyl Diphosphate Synthase Activity Metal Ion Binding	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Dolichyl Diphosphate Biosynthetic Process Polyprenol Biosynthetic Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Response To Organic Cyclic Compound Mitochondrial Respiratory Chain Complex I Assembly Response To Hydroperoxide Response To Drug
Pathways		Synthesis of Dolichyl-phosphate Defective DHDDS causes retinitis pigmentosa 59	Respiratory electron transport Complex I biogenesis
Drugs			NADH Methoxyflurane Halothane Desflurane Sevoflurane N-Formylmethionine Phenethyl Isothiocyanate
Diseases			Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS		FEV1 ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		3 interacting genes: LOX MT-ND1 NPC2	12 interacting genes: BARD1 BRCA1 DHDDS FAT1 LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 SIRPA TST
Entrez ID		79947	4535
HPRD ID		12183	08365
Ensembl ID		ENSG00000117682	ENSG00000198888
Uniprot IDs		Q86SQ9	P03886 U5Z754
PDB IDs		6W2L 6Z1N	5XTC 5XTD
Enriched GO Terms of Interacting Partners?
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