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MT-ND1

Description NADH dehydrogenase subunit 1
Image
GO Annotations Cellular Component
  • Mitochondrial Inner Membrane
  • Mitochondrial Respiratory Chain Complex I
  • Integral Component Of Membrane
  • Dendrite
  • Mitochondrial Membrane
  • Neuronal Cell Body
Molecular Function
  • NADH Dehydrogenase Activity
  • Protein Binding
  • NADH Dehydrogenase (ubiquinone) Activity
Biological Process
  • Mitochondrial Electron Transport, NADH To Ubiquinone
  • Aerobic Respiration
  • Response To Organic Cyclic Compound
  • Mitochondrial Respiratory Chain Complex I Assembly
  • Response To Hydroperoxide
  • Response To Drug
Pathways
  • Respiratory electron transport
  • Complex I biogenesis
Drugs
  • NADH
  • Methoxyflurane
  • Halothane
  • Desflurane
  • Sevoflurane
  • N-Formylmethionine
  • Phenethyl Isothiocyanate
Diseases
  • Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Interacting Genes 12 interacting genes: BARD1 BRCA1 DHDDS FAT1 LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 SIRPA TST
Entrez ID 4535
HPRD ID 08365
Ensembl ID ENSG00000198888
Uniprot IDs P03886 U5Z754
PDB IDs 5XTC 5XTD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025