RPP21 and RPP38

Data Source:
HPRD (two hybrid)

		RPP21	RPP38
Description		ribonuclease P/MRP subunit p21	ribonuclease P/MRP subunit p38
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GO Annotations	Cellular Component	Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex	Fibrillar Center Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease P Activity Ribonuclease P RNA Binding Metal Ion Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal TRNA Processing Response To Drug RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Moderate to vigorous physical activity levels ( 29899525) Neurociticism ( 29500382) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848)	Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		3 interacting genes: RPP30 RPP38 RPP40	9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40
Entrez ID		79897	10557
HPRD ID		15275	09360
Ensembl ID		ENSG00000241370	ENSG00000152464
Uniprot IDs		A0A1U9X8H3 Q9H633	P78345
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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