ZYG11B and CFL2

		ZYG11B	CFL2
Description		zyg-11 family member B, cell cycle regulator	cofilin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cul2-RING Ubiquitin Ligase Complex	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Actin Filament Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing
Pathways
Drugs
Diseases			Nemaline myopathy
GWAS		Monocyte percentage of white cells ( 32888494)	Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		4 interacting genes: CUL2 ELOB ELOC GBF1	13 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I
Entrez ID		79699	1073
HPRD ID		13356	03262
Ensembl ID		ENSG00000162378	ENSG00000165410
Uniprot IDs		A8DPD7 B4DK95 Q9C0D3	Q549N0 Q9Y281
PDB IDs
Enriched GO Terms of Interacting Partners?
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