ZMAT4 and CUL4B

Data Source:
BioGRID (two hybrid)

		ZMAT4	CUL4B
Description		zinc finger matrin-type 4	cullin 4B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytosol SCF Ubiquitin Ligase Complex Cullin-RING Ubiquitin Ligase Complex Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Exosome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Damaged DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process		G1/S Transition Of Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Stabilization Nucleotide-excision Repair, Preincision Complex Assembly Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Cellular Response To DNA Damage Stimulus Proteasomal Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleotide-excision Repair, DNA Incision Histone H2A Monoubiquitination Ribosome Biogenesis DNA Damage Response, Detection Of DNA Damage Post-translational Protein Modification Global Genome Nucleotide-excision Repair UV-damage Excision Repair
Pathways			Recognition of DNA damage by PCNA-containing replication complex DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation
Drugs
Diseases			Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS		Body fat mass ( 28552196) Brain volume in infants (grey matter) ( 28763065) Coffee consumption ( 31046077) Fasting plasma glucose ( 17903298) Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) Hip circumference ( 28552196) Iris color (L* coordinate) ( 30895295) Lung cancer ( 28604730) Myopia ( 27182965) Pediatric areal bone mineral density (concordant skeletal phenotype) ( 29240982) Refractive error ( 23396134 32231278) Severe aplastic anemia ( 32004448) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist circumference ( 28552196)
Interacting Genes		10 interacting genes: ADARB1 APP CUL3 CUL4B DAPK1 LRSAM1 PRKRA SRPK2 STRBP TARBP2	25 interacting genes: AHR APP AR CAND1 COMMD1 DCUN1D4 DDB1 DDB2 DNMT3B ESR1 HUWE1 KPNA2 KPNA4 KPNB1 NEDD8 PRDX3 PTEN RBX1 RNF7 SALL2 SIN3A TBL3 UBC UBE2D3 ZMAT4
Entrez ID		79698	8450
HPRD ID		07837	02251
Ensembl ID		ENSG00000165061	ENSG00000158290
Uniprot IDs		Q9H898	K4DI93 Q13620
PDB IDs			2DO7 4A0C 4A0L 4A64
Enriched GO Terms of Interacting Partners?
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