Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
HSPBAP1 and ARHGEF5
Data Source:
BioGRID
(two hybrid, two hybrid)
HSPBAP1
ARHGEF5
Description
HSPB1 associated protein 1
Rho guanine nucleotide exchange factor 5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Podosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Cell Junction
Cell Projection
Cell Periphery
Molecular Function
Protein Binding
2-oxoglutarate-dependent Dioxygenase Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
GTP Binding
Lipid Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Regulation Of Actin Cytoskeleton Organization
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Regulation Of GTPase Activity
Positive Regulation Of JUN Kinase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of DNA-binding Transcription Factor Activity
Regulation Of Cytoskeleton Organization
Positive Regulation Of Stress Fiber Assembly
Regulation Of ERK1 And ERK2 Cascade
Activation Of GTPase Activity
Positive Regulation Of Protein Import
Pathways
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events
Drugs
Diseases
GWAS
Breast cancer (
23535729
)
Breast cancer, ovarian cancer or prostate cancer (pleiotropy) (
27432226
)
Gut microbiota relative abundance (Parabacteroides) (
33208821
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Interacting Genes
5 interacting genes:
ARHGEF5
NUTM1
PTN
RIPK3
TK1
28 interacting genes:
APP
ATP13A1
CALCOCO2
CCNE1
CHPF
COG6
EFHC2
EPM2AIP1
FKBP8
HSF2BP
HSPBAP1
LMO2
LRATD1
MB21D2
MID2
NR4A1
PICK1
PLCG1
PLEKHG4
POLR1C
RHOA
SEPHS2
SLAIN1
TBC1D13
TCF4
TRIM27
TRIM54
ZRANB1
Entrez ID
79663
7984
HPRD ID
12197
02932
Ensembl ID
ENSG00000169087
ENSG00000050327
Uniprot IDs
A8K045
Q96EW2
Q12774
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?