FAM184A and LRRK1

Data Source:
BioGRID (pull down)

		FAM184A	LRRK1
Description		family with sequence similarity 184 member A	leucine rich repeat kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Cytoplasm Mitochondrion Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding	Protein Serine/threonine Phosphatase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Biological_process	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Parkinson's disease progression (composite) ( 33111402) Parkinson's disease progression (motor) ( 33111402) Schizophrenia ( 30285260)	Central corneal thickness ( 32528159 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196)
Interacting Genes		11 interacting genes: AMOTL2 APP BRAP BRCA1 GOLGA2 LRRK1 LRRK2 MAP3K1 MTDH PPP1R13B VPS52	51 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP VGLL4
Entrez ID		79632	79705
HPRD ID		09856	14319
Ensembl ID		ENSG00000111879	ENSG00000154237
Uniprot IDs		H7BY63 Q6P9G8 Q8NB25	Q38SD2
PDB IDs
Enriched GO Terms of Interacting Partners?
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