SPAG16 and MEIG1

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SPAG16	MEIG1
Description		sperm associated antigen 16	meiosis/spermiogenesis associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Axoneme Sperm Flagellum Axonemal Central Apparatus	Manchette Nucleus Cytosol
	Molecular Function		Protein Binding
	Biological Process	Sperm Axoneme Assembly Axoneme Assembly Cilium Assembly Cerebrospinal Fluid Circulation Mucociliary Clearance	Sperm Axoneme Assembly Cellular Protein Localization Manchette Assembly
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 30478444) Body mass index ( 25673413) Contrast sensitivity ( 24152035) Fasting insulin (dietary factor interaction) ( 24204828) HIV-associated neurocognitive disorder (mild neurocognitive disorder) ( 28447399) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Initial pursuit acceleration ( 29064472) Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Schizophrenia ( 30285260) Waist circumference ( 28552196)	Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		5 interacting genes: AP3M1 MEIG1 MRPL1 SPAG6 VEZF1	3 interacting genes: NCOA5 PACRG SPAG16
Entrez ID		79582	644890
HPRD ID		18089	18975
Ensembl ID		ENSG00000144451	ENSG00000197889
Uniprot IDs		B4DYB5 Q4G1A2 Q8N0X2	Q5JSS6
PDB IDs			6NDU 6NEP 6UCC
Enriched GO Terms of Interacting Partners?
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