MEIG1 and NCOA5

Data Source:
BioGRID (two hybrid)

		MEIG1	NCOA5
Description		meiosis/spermiogenesis associated 1	nuclear receptor coactivator 5
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GO Annotations	Cellular Component	Manchette Nucleus Cytosol	Extracellular Space Nucleoplasm Actin Cytoskeleton
	Molecular Function	Protein Binding	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process	Sperm Axoneme Assembly Cellular Protein Localization Manchette Assembly	Negative Regulation Of Transcription By RNA Polymerase II Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways
Drugs			17alpha-Estriol
Diseases
GWAS		Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) HDL cholesterol levels ( 32203549) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)
Interacting Genes		3 interacting genes: NCOA5 PACRG SPAG16	19 interacting genes: ACOT7 CCDC57 CDC37 FAM214B GORASP2 HTATIP2 KANK2 KHDRBS2 KHDRBS3 MEIG1 NR1D2 NTAQ1 PICK1 RAB30 SYT16 TSC22D1 TSGA10IP UBL5 ZNF326
Entrez ID		644890	57727
HPRD ID		18975	14813
Ensembl ID		ENSG00000197889	ENSG00000124160
Uniprot IDs		Q5JSS6	Q9HCD5
PDB IDs		6NDU 6NEP 6UCC	1V95 2J7X 2J7Y 4ZI1
Enriched GO Terms of Interacting Partners?
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