NKAP and DHX15

Data Source:
BioGRID (two hybrid)

		NKAP	DHX15
Description		NFKB activating protein	DEAH-box helicase 15
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus Nuclear Speck U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	Chromatin Binding RNA Binding Protein Binding	RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Alpha-beta T Cell Differentiation	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Toxic Substance Response To Alkaloid
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Myopia (pathological) ( 23049088) Pulmonary emphysema ( 24383474) Sense of smell ( 26632684)
Interacting Genes		18 interacting genes: AP1M1 CEP70 DHX15 DHX8 FAM124A FRA10AC1 LUC7L2 PCBP2 PPIG PRPF3 PRPF40A RBM39 RBMX2 SRPK1 SRPK2 THAP1 TTC14 U2AF1	21 interacting genes: AGGF1 APBB1 CAMSAP3 DDX42 DYSF FXR1 GPANK1 KRT75 NKAP NKRF PIN1 PRPF40A PTEN RBM17 SPOP TRA2A UBC WBP4 YWHAB YWHAG ZGPAT
Entrez ID		79576	1665
HPRD ID		06666	04553
Ensembl ID		ENSG00000101882	ENSG00000109606
Uniprot IDs		Q8N5F7	O43143
PDB IDs		6QDV	5XDR 6ID1 6SH6 6SH7
Enriched GO Terms of Interacting Partners?
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