DDX39B and DDX39A

Data Source:
HPRD (two hybrid)

		DDX39B	DDX39A
Description		DExD-box helicase 39B	DExD-box helicase 39A
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Matrix Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Speck
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity ATPase Activity U6 SnRNA Binding U4 SnRNA Binding Identical Protein Binding ATP-dependent Protein Binding Protein-containing Complex Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Liver Development RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding MRNA 3'-end Processing Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Translation Viral MRNA Export From Host Cell Nucleus Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of DNA Damage Checkpoint Positive Regulation Of DNA Biosynthetic Process	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Artenimol
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 32888494) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Mean platelet volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 27863252) Mosquito bite size ( 28199695) Myositis ( 26291516) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		31 interacting genes: ALYREF BARD1 CHTOP DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R LUZP4 NCBP2 PIAS2 RBM39 RNF4 RPS15A SARNP SDCBP SNRPA SREK1 SRPK2 STRN4 SUMO2 TDG THOC3 THOC6 TUBB3 U2AF2 UBE2I YWHAG ZHX1	14 interacting genes: CCL14 CHTOP DDX39B EXOSC9 HIPK2 HNRNPLL PTK2 RNF4 SARNP SAT1 SUMO2 TERF1 TERF2IP UBE2I
Entrez ID		7919	10212
HPRD ID		00805	10861
Ensembl ID		ENSG00000198563	ENSG00000123136
Uniprot IDs		A0A024RCM3 Q13838	O00148
PDB IDs		1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?
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