WDR77 and PITRM1

Data Source:
BioGRID (affinity chromatography technology)

		WDR77	PITRM1
Description		WD repeat domain 77	pitrilysin metallopeptidase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome Pole Plasm	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Methyl-CpG Binding Nuclear Receptor Coactivator Activity	Metalloendopeptidase Activity Enzyme Activator Activity Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Pole Plasm Assembly Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription, DNA-templated Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development	Proteolysis Protein Targeting To Mitochondrion Protein Processing Regulation Of Catalytic Activity
Pathways		snRNP Assembly RMTs methylate histone arginines	Mitochondrial protein import
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)
Interacting Genes		44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZMYND19 ZNF207
Entrez ID		79084	10531
HPRD ID		14387	07142
Ensembl ID		ENSG00000116455	ENSG00000107959
Uniprot IDs		A0A024R0H7 Q9BQA1	Q5JRX3
PDB IDs		4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S 6RLL 6RLQ 6UXX 6UXY 6V0N 6V0O	4L3T 4NGE 4RPU
Enriched GO Terms of Interacting Partners?
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