MALL and NEK9

Data Source:
BioGRID (affinity chromatography technology)

		MALL	NEK9
Description		mal, T cell differentiation protein like	NIMA related kinase 9
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft	Nucleus Centrosome Cytosol
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Myelination Cholesterol Homeostasis	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Cell Division
Pathways			Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs			Fostamatinib
Diseases
GWAS			Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)
Interacting Genes		68 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35C2 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I ZP3	10 interacting genes: BICD2 CSN2 MBP NEK6 NEK7 NEK8 RAN SSRP1 SUPT16H TTN
Entrez ID		7851	91754
HPRD ID		15997	11386
Ensembl ID		ENSG00000144063	ENSG00000119638
Uniprot IDs		Q13021	Q6PKF2 Q8TD19
PDB IDs			3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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