ZMYM2 and UBE2A

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		ZMYM2	UBE2A
Description		zinc finger MYM-type containing 2	ubiquitin conjugating enzyme E2 A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol PML Body	Chromatin XY Body Nucleoplasm Cytosol HULC Complex
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Biological_process	Protein Polyubiquitination Blastocyst Hatching DNA Repair Postreplication Repair Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell Population Proliferation Response To UV Protein Ubiquitination Histone Ubiquitination Histone H2A Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Maternal Process Involved In Female Pregnancy Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Synthesis of active ubiquitin: roles of E1 and E2 enzymes E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)	Brain connectivity ( 23471985)
Interacting Genes		26 interacting genes: CEBPE CREB1 CREBBP FBXL17 FUS GMCL1 HNRNPA2B1 HNRNPH3 IKZF3 PAICS PTBP1 RCOR1 SFPQ SKIL SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 SUMO2 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B	26 interacting genes: CBX5 CDK1 CDK2 CDK9 CDKN2A CRMP1 EEF1D H2BC21 HLTF KCMF1 MDM2 PCNA PRKN RAD18 RC3H1 RNF20 RNF4 RNF40 SDCBP TP53 TRIM27 UBA1 UBR1 UBR3 UBR5 ZMYM2
Entrez ID		7750	7319
HPRD ID		03745	02422
Ensembl ID		ENSG00000121741	ENSG00000077721
Uniprot IDs		A0A024RDS3 A8K126 Q9UBW7	A0A0D9SG71 P49459
PDB IDs			6CYO 6CYR
Enriched GO Terms of Interacting Partners?
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