VEZF1 and SPAG16

Data Source:
BioGRID (two hybrid)

		VEZF1	SPAG16
Description		vascular endothelial zinc finger 1	sperm associated antigen 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Region Axoneme Sperm Flagellum Axonemal Central Apparatus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Angiogenesis Endothelial Cell Development Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Sperm Axoneme Assembly Axoneme Assembly Cilium Assembly Cerebrospinal Fluid Circulation Mucociliary Clearance
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 30478444) Body mass index ( 25673413) Contrast sensitivity ( 24152035) Fasting insulin (dietary factor interaction) ( 24204828) HIV-associated neurocognitive disorder (mild neurocognitive disorder) ( 28447399) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Initial pursuit acceleration ( 29064472) Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Schizophrenia ( 30285260) Waist circumference ( 28552196)
Interacting Genes		65 interacting genes: AGR2 ATXN7L1 BANP C10orf55 CEACAM6 CEP76 DAZAP2 EHMT2 FAM153B FAM168B FOSB FSD2 GOLGA6L9 GPSM1 HIVEP1 HOMEZ HSF2BP HSPB2 HSPB2-C11orf52 INCA1 KCTD7 KRT40 KRTAP10-8 KRTAP19-5 KRTAP8-1 LASP1 LCN2 LHX3 LMO2 LZTS2 MEIS3 MEOX2 MLLT10 MSX2 NCKIPSD NFYA NRF1 PFDN5 PICK1 PLAGL2 POGZ POU6F2 PRKAR1B PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS RUBCN SF3A2 SOX13 SP4 SPAG16 TLE5 TRAF1 TRAF2 TRIM27 TSC1 UBE2I VBP1 VPS52 WWOX ZMYND12 ZRANB1	5 interacting genes: AP3M1 MEIG1 MRPL1 SPAG6 VEZF1
Entrez ID		7716	79582
HPRD ID		08416	18089
Ensembl ID		ENSG00000136451	ENSG00000144451
Uniprot IDs		J3QSH4 Q14119	B4DYB5 Q4G1A2 Q8N0X2
PDB IDs
Enriched GO Terms of Interacting Partners?
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