CA12 and SGSM2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CA12	SGSM2
Description		carbonic anhydrase 12	small G protein signaling modulator 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Cytoplasm Melanosome
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding Hydro-lyase Activity	GTPase Activator Activity Small GTPase Binding
	Biological Process	One-carbon Metabolic Process Bicarbonate Transport Chloride Ion Homeostasis	Intracellular Protein Transport Late Endosome To Golgi Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity
Pathways		Reversible hydration of carbon dioxide
Drugs		Benzthiazide Hydroflumethiazide Acetazolamide Zonisamide Ellagic acid
Diseases
GWAS		Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Refractive error ( 32231278)	Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fasting blood proinsulin levels ( 23263489) Household income (MTAG) ( 31844048) Insulin-related traits (multivariate analysis) ( 32002517) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Proinsulin levels ( 21873549) Schizophrenia ( 25056061)
Interacting Genes		10 interacting genes: ATP5F1C CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1	20 interacting genes: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 MTDH PNO1 PTN RAB2A RAB2B RAB3A RAB3B RAB9B RGMA RPS25
Entrez ID		771	9905
HPRD ID		04464	15284
Ensembl ID		ENSG00000074410	ENSG00000141258
Uniprot IDs		B3KUB4 O43570	B9A6J3 O43147
PDB IDs		1JCZ 1JD0 4HT2 4KP5 4KP8 4Q0L 4QJ0 4QJO 4QJW 4WW8 5LL5 5LL9 5LLO 5LLP 5MSA 5MSB 6G5L 6G7A 6QN0 6QNG 6QNL 6R6Y 6R71 6RPS 6T5P 6T5Q
Enriched GO Terms of Interacting Partners?
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