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SGSM2 and RAB3A
Data Source:
BioGRID
(two hybrid)
SGSM2
RAB3A
Description
small G protein signaling modulator 2
RAB3A, member RAS oncogene family
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Melanosome
Acrosomal Vesicle
Lysosome
Endosome
Cytosol
Plasma Membrane
Synaptic Vesicle
Axon
Secretory Granule Membrane
Protein-containing Complex
Terminal Bouton
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone
Clathrin-sculpted Acetylcholine Transport Vesicle Membrane
Clathrin-sculpted Glutamate Transport Vesicle Membrane
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Clathrin-sculpted Monoamine Transport Vesicle Membrane
Anchored Component Of Synaptic Vesicle Membrane
Extracellular Vesicle
Molecular Function
GTPase Activator Activity
Small GTPase Binding
ATPase Activator Activity
GTPase Activity
Protein Binding
GTP Binding
Protein C-terminus Binding
GTP-dependent Protein Binding
Myosin V Binding
GDP-dissociation Inhibitor Binding
ATPase Binding
Biological Process
Intracellular Protein Transport
Late Endosome To Golgi Transport
Positive Regulation Of GTPase Activity
Activation Of GTPase Activity
Plasma Membrane Repair
Respiratory System Process
Exocytosis
Vesicle Docking Involved In Exocytosis
Mitochondrion Organization
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Axonogenesis
Protein Secretion
Post-embryonic Development
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Regulation Of Dopamine Secretion
Synaptic Vesicle Exocytosis
Synaptic Vesicle Maturation
Regulation Of Exocytosis
Lung Development
Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Lysosome Localization
Positive Regulation Of ATPase Activity
Synaptic Vesicle Recycling
Neutrophil Degranulation
Post-translational Protein Modification
Constitutive Secretory Pathway
Regulated Exocytosis
Positive Regulation Of Exocytosis
Regulation Of Short-term Neuronal Synaptic Plasticity
Synaptic Vesicle Transport
Maintenance Of Presynaptic Active Zone Structure
Sensory Perception Of Touch
Response To Electrical Stimulus
Acrosomal Vesicle Exocytosis
Evoked Neurotransmitter Secretion
Protein Localization To Plasma Membrane
Synaptic Vesicle Clustering
Positive Regulation Of Regulated Secretory Pathway
Regulation Of Plasma Membrane Repair
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS
Aortic root size (
19584346
)
Autism spectrum disorder or schizophrenia (
28540026
)
Brain morphology (MOSTest) (
32665545
)
Fasting blood proinsulin levels (
23263489
)
Household income (MTAG) (
31844048
)
Insulin-related traits (multivariate analysis) (
32002517
)
Multiple sclerosis (
31604244
)
Number of sexual partners (
30643258
)
Proinsulin levels (
21873549
)
Schizophrenia (
25056061
)
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Interacting Genes
20 interacting genes:
AFP
CA12
CELSR3
CHD3
EGFR
FNBP1L
GDPD2
ILF2
KHDRBS3
MPP1
MTDH
PNO1
PTN
RAB2A
RAB2B
RAB3A
RAB3B
RAB9B
RGMA
RPS25
29 interacting genes:
A2M
ADRB2
AP1M2
APP
CASK
CHM
CHML
CHRM4
DMXL2
ECSIT
EGFR
KRTAP10-8
MAST1
MYO5A
PSEN1
RAB3IL1
RAB3IP
RABAC1
RABGGTB
RABIF
RIMS1
RIMS2
RNF32
RPH3A
RPH3AL
SGSM2
SYTL4
SYTL5
VRTN
Entrez ID
9905
5864
HPRD ID
15284
01535
Ensembl ID
ENSG00000141258
ENSG00000105649
Uniprot IDs
B9A6J3
O43147
A0A024R7I7
P20336
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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