ZNF32 and CHMP2A

Data Source:
BioGRID (proximity labelling technology)

		ZNF32	CHMP2A
Description		zinc finger protein 32	charged multivesicular body protein 2A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin ESCRT III Complex Nuclear Envelope Multivesicular Body Cytosol Membrane Membrane Coat Late Endosome Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Protein Domain Specific Binding Phosphatidylcholine Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Regulation Of Viral Process Protein Polymerization Protein Homooligomerization Negative Regulation Of Cell Death Midbody Abscission Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Macroautophagy Lysosome Vesicle Biogenesis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254)	Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		12 interacting genes: CARD10 CCDC125 GOLGA6L9 INCA1 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-8 NOTCH2NLA POT1 ULK2	13 interacting genes: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 UFD1 USP54 USP8 VPS4A VPS4B
Entrez ID		7580	27243
HPRD ID		01924	12520
Ensembl ID		ENSG00000169740	ENSG00000130724
Uniprot IDs		A0A024R7T7 P17041	A0A024R4S0 O43633
PDB IDs		2EPC 2EPT 2EPU 2YTA 2YTB
Enriched GO Terms of Interacting Partners?
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