FMNL1 and GAS7

Data Source:
BioGRID (pull down)

		FMNL1	GAS7
Description		formin like 1	growth arrest specific 7
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Cortex Membrane Bleb Phagocytic Vesicle Extracellular Exosome	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane
	Molecular Function	Molecular_function Protein Binding Small GTPase Binding GTPase Activating Protein Binding Actin Filament Binding	Protein Binding Actin Filament Binding
	Biological Process	Regulation Of Cell Shape Cell Migration Cortical Actin Cytoskeleton Organization Actin Filament Severing	Actin Filament Polymerization Neuron Projection Morphogenesis
Pathways		RHO GTPases Activate Formins RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Craniofacial microsomia ( 26853712) Hypothyroidism ( 30367059) Male-pattern baldness ( 28196072) Thyroid stimulating hormone levels ( 30367059)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Glaucoma ( 30104761 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935) Gut microbiota relative abundance (Prevotella) ( 33208821) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 25173106 24002674 22570627 31798171 29785010 31959993 30054594 28073927 29235454) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)
Interacting Genes		11 interacting genes: APP GAS7 HMG20A PFN1 PFN2 PRPF40A RAC1 SRPK2 TCERG1 TRIM54 XRCC6	26 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CDC37 CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 LSM4 MCRS1 MYBPC2 NCKAP1 NCKAP1L NCKIPSD NTAQ1 PACSIN1 RPLP0 SF1 SF3A1 SFPQ WASF2 YIF1A
Entrez ID		752	8522
HPRD ID		06876	16011
Ensembl ID		ENSG00000184922	ENSG00000007237
Uniprot IDs		O95466	O60861
PDB IDs		4YDH	2LX7 2YSH
Enriched GO Terms of Interacting Partners?
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