DAGLA and TIMM10

Data Source:
BioGRID (enzymatic study)

		DAGLA	TIMM10
Description		diacylglycerol lipase alpha	translocase of inner mitochondrial membrane 10
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Early Endosome Membrane Dendrite Membrane Dendritic Spine Membrane Varicosity Postsynaptic Membrane Postsynaptic Density Membrane Integral Component Of Postsynaptic Membrane	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex
	Molecular Function	Protein Binding Hydrolase Activity Metal Ion Binding	Protein Binding Zinc Ion Binding Protein Homodimerization Activity Chaperone Binding Protein Transporter Activity
	Biological Process	G Protein-coupled Glutamate Receptor Signaling Pathway Neuroblast Proliferation Arachidonic Acid Metabolic Process Neurogenesis Neurotransmitter Biosynthetic Process Diacylglycerol Catabolic Process Endocannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid Regulation Of Neuroinflammatory Response	Protein Targeting To Mitochondrion Sensory Perception Of Sound Protein Insertion Into Mitochondrial Inner Membrane Chaperone-mediated Protein Transport
Pathways		Arachidonate production from DAG	Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744 31043756) Immune reponse to smallpox (secreted IL-2) ( 22610502) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Refractive error ( 32231278)	Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		10 interacting genes: CMTM7 LHFPL5 MAL MALL MS4A13 STOM TMEM218 TRARG1 UPK1B VMA21	3 interacting genes: SIK1B TBC1D21 ZNF655
Entrez ID		747	26519
HPRD ID		07092	03768
Ensembl ID		ENSG00000134780	ENSG00000134809
Uniprot IDs		Q9Y4D2	P62072
PDB IDs			2BSK 7CGP
Enriched GO Terms of Interacting Partners?
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