DAGLA and CMTM7

Data Source:
BioGRID (two hybrid)

		DAGLA	CMTM7
Description		diacylglycerol lipase alpha	CKLF like MARVEL transmembrane domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Early Endosome Membrane Dendrite Membrane Dendritic Spine Membrane Varicosity Postsynaptic Membrane Postsynaptic Density Membrane Integral Component Of Postsynaptic Membrane	Extracellular Space Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Hydrolase Activity Metal Ion Binding	Cytokine Activity Protein Binding
	Biological Process	G Protein-coupled Glutamate Receptor Signaling Pathway Neuroblast Proliferation Arachidonic Acid Metabolic Process Neurogenesis Neurotransmitter Biosynthetic Process Diacylglycerol Catabolic Process Endocannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid Regulation Of Neuroinflammatory Response	B-1a B Cell Differentiation Chemotaxis Signal Transduction
Pathways		Arachidonate production from DAG
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744 31043756) Immune reponse to smallpox (secreted IL-2) ( 22610502) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Refractive error ( 32231278)	Copper levels ( 26025379) Hallux valgus ( 32131869) IgM levels ( 28628107) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		10 interacting genes: CMTM7 LHFPL5 MAL MALL MS4A13 STOM TMEM218 TRARG1 UPK1B VMA21	47 interacting genes: ADTRP AGER AQP6 ARL13B B3GAT1 BIK BSCL2 CD74 CD79A CLSTN3 CREB3L1 DAGLA DNAJC1 ELOVL4 FAM174A FAM209A FFAR2 FRMD3 GGT7 GORAB HAS3 HIBADH HSD17B13 LDLRAD1 LHFPL5 LMNA MS4A4A MUC1 PAGE1 PIANP PSMD6 RETREG3 SDC3 SHISA3 SLC14A2 SLC30A8 SSMEM1 STX1A TCTA TEX29 THAP4 TMEM106C TMEM174 TMEM31 TMPRSS2 TMX2 TNFRSF17
Entrez ID		747	112616
HPRD ID		07092	06988
Ensembl ID		ENSG00000134780	ENSG00000153551
Uniprot IDs		Q9Y4D2	F8WDZ3 Q96FZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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