DAGLA and LHFPL5

Data Source:
BioGRID (two hybrid)

		DAGLA	LHFPL5
Description		diacylglycerol lipase alpha	LHFPL tetraspan subfamily member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Early Endosome Membrane Dendrite Membrane Dendritic Spine Membrane Varicosity Postsynaptic Membrane Postsynaptic Density Membrane Integral Component Of Postsynaptic Membrane	Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane Stereocilium Tip
	Molecular Function	Protein Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	G Protein-coupled Glutamate Receptor Signaling Pathway Neuroblast Proliferation Arachidonic Acid Metabolic Process Neurogenesis Neurotransmitter Biosynthetic Process Diacylglycerol Catabolic Process Endocannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid Regulation Of Neuroinflammatory Response	Ion Transport Sensory Perception Of Sound Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Detection Of Mechanical Stimulus Involved In Sensory Perception Auditory Receptor Cell Stereocilium Organization
Pathways		Arachidonate production from DAG
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744 31043756) Immune reponse to smallpox (secreted IL-2) ( 22610502) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Refractive error ( 32231278)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494)
Interacting Genes		10 interacting genes: CMTM7 LHFPL5 MAL MALL MS4A13 STOM TMEM218 TRARG1 UPK1B VMA21	127 interacting genes: ADGRG3 APOL3 AQP2 AQP6 AQP9 BTN2A2 C14orf180 C1GALT1 C3orf52 C5orf46 CD37 CD53 CD72 CD79A CD81 CDS2 CERS4 CLCN7 CLDN22 CLDN5 CLDND2 CLEC14A CMTM7 CREB3 CREB3L1 CTXN3 CXCL16 CYB561 DAGLA ELOVL4 EMP1 EMP3 ENTPD3 ERG28 ERGIC3 FAM209A FCGR1A FFAR2 FNDC9 FXYD6 GGT7 GJA8 GJB2 GJB3 GJB4 GJB6 GPR152 GPR37L1 GPR42 GPRC5D GPX8 HAS3 HLA-DQA2 INSIG2 ITGB2 JAGN1 KASH5 KCNK5 KIR2DL3 KTN1 LAT LIME1 LMNA LNPEP LPAR3 LRRC25 LRRC4C MFF MFSD5 MIP MS4A13 MTIF3 NINJ2 NIPAL4 NKG7 NRG4 PDZK1IP1 PLLP PLP1 PLP2 RMDN3 RPRM RUSF1 SAR1A SEC22A SEC22B SERP1 SERP2 SERTM1 SLC16A2 SLC34A2 SLC35A1 SLC35B4 SLC35C2 SLC41A1 SMIM1 SYNJ2BP TEX264 TFRC TIMMDC1 TM4SF18 TM4SF4 TMEM100 TMEM107 TMEM128 TMEM201 TMEM218 TMEM229B TMEM248 TMEM254 TMEM31 TMEM42 TMEM50B TMEM52B TMEM60 TMEM86A TMEM97 TMX1 TMX2 TRARG1 TSPAN33 TSPAN7 TSPO UBIAD1 VAMP3 VMA21 ZDHHC15
Entrez ID		747	222662
HPRD ID		07092	13989
Ensembl ID		ENSG00000134780	ENSG00000197753
Uniprot IDs		Q9Y4D2	Q8TAF8
PDB IDs
Enriched GO Terms of Interacting Partners?
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