EIF4H and C11orf68

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		EIF4H	C11orf68
Description		eukaryotic translation initiation factor 4H	chromosome 11 open reading frame 68
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding RNA Strand Annealing Activity RNA Strand-exchange Activity Ribosomal Small Subunit Binding Cadherin Binding	RNA Binding Protein Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translational Initiation Regulation Of Translational Initiation Viral Process Sexual Reproduction Developmental Growth Eukaryotic Translation Initiation Factor 4F Complex Assembly
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Asthma ( 31959851)
Interacting Genes		7 interacting genes: C11orf68 DDIT4L DLG3 FBXO17 LNX1 PICK1 SPG21	14 interacting genes: CSDE1 EIF4H KCNE3 KLF15 MEOX2 MTCL1 NONO PHETA1 REL SDCBP SH3GL3 TRAPPC2L ZNF341 ZNF512B
Entrez ID		7458	83638
HPRD ID		11940	12553
Ensembl ID		ENSG00000106682	ENSG00000175573
Uniprot IDs		Q15056	Q9H3H3
PDB IDs			1ZTP 2Q4K
Enriched GO Terms of Interacting Partners?
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