WIPF1 and FASTK

Data Source:
BioGRID (two hybrid)

		WIPF1	FASTK
Description		WAS/WASL interacting protein family member 1	Fas activated serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytosol Actin Filament Actin Cytoskeleton Cytoplasmic Vesicle	Mitochondrial Matrix
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Fas-activated Serine/threonine Kinase Activity
	Biological Process	Actin Polymerization Or Depolymerization Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Response To Other Organism Protein-containing Complex Assembly	Protein Phosphorylation Regulation Of RNA Splicing Regulation Of Mitochondrial MRNA Stability Apoptotic Signaling Pathway
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)	Eyebrow thickness ( 26926045)
Interacting Genes		26 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CACNG2 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 NCK2 PRKCQ PRPF40A RER1 SEC24C SH3RF1 WAS WASL WBP4 WWP2 ZAP70	9 interacting genes: CALCOCO2 CHERP ESRRG MDFI PRPF31 RBPMS TIA1 TOP3B WIPF1
Entrez ID		7456	10922
HPRD ID		03835	07368
Ensembl ID		ENSG00000115935	ENSG00000164896
Uniprot IDs		A0A140VJZ9 O43516 Q2YDC4	A0A090N8I0 A0A090N8Z7 Q14296
PDB IDs		2A41
Enriched GO Terms of Interacting Partners?
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