FASTK and TIA1

Data Source:
HPRD (in vivo, in vitro)

		FASTK	TIA1
Description		Fas activated serine/threonine kinase	TIA1 cytotoxic granule associated RNA binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Stress Granule Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Fas-activated Serine/threonine Kinase Activity	RNA Binding Protein Binding Poly(A) Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Protein Phosphorylation Regulation Of RNA Splicing Regulation Of Mitochondrial MRNA Stability Apoptotic Signaling Pathway	Negative Regulation Of Cytokine Production Apoptotic Process Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Protein Localization To Cytoplasmic Stress Granule Positive Regulation Of Epithelial Cell Apoptotic Process
Pathways			FGFR2 alternative splicing
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		9 interacting genes: CALCOCO2 CHERP ESRRG MDFI PRPF31 RBPMS TIA1 TOP3B WIPF1	2 interacting genes: FASTK WBP4
Entrez ID		10922	7072
HPRD ID		07368	04626
Ensembl ID		ENSG00000164896	ENSG00000116001
Uniprot IDs		A0A090N8I0 A0A090N8Z7 Q14296	P31483
PDB IDs			2MJN 3BS9 5ITH 5O2V 5O3J 6ELD
Enriched GO Terms of Interacting Partners?
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