VTN and ADTRP

Data Source:
BioGRID (two hybrid)

		VTN	ADTRP
Description		vitronectin	androgen dependent TFPI regulating protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Extracellular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle	Caveola Cell Surface Membrane Integral Component Of Membrane
	Molecular Function	Scavenger Receptor Activity Integrin Binding Extracellular Matrix Structural Constituent Protein Binding Heparin Binding Polysaccharide Binding	Protein Binding Hydrolase Activity
	Biological Process	Endocytosis Immune Response Cell Adhesion Cell-matrix Adhesion Negative Regulation Of Endopeptidase Activity Positive Regulation Of Smooth Muscle Cell Migration Cell Migration Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Regulation Of Complement Activation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Binding Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing	Positive Regulation Of Protein Phosphorylation Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Leukocyte Migration Negative Regulation Of Extracellular Matrix Constituent Secretion Positive Regulation Of Gene Expression Negative Regulation Of Blood Coagulation Long-chain Fatty Acid Catabolic Process Protein Kinase B Signaling Negative Regulation Of Protein Secretion Cellular Response To Steroid Hormone Stimulus Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration
Pathways		Molecules associated with elastic fibres Integrin cell surface interactions Syndecan interactions ECM proteoglycans ECM proteoglycans Regulation of Complement cascade
Drugs		Abciximab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488 28240269) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Low density lipoprotein cholesterol levels ( 32154731) Osteoprotegerin levels ( 25080503)	Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Daytime sleep phenotypes ( 27126917) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Refractive error ( 32231278) Simvastatin-induced myopathy ( 31220337) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Spatial processing ( 31596458) Thrombosis ( 26908601)
Interacting Genes		47 interacting genes: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 DLG2 DLG3 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA8 ITGB3 ITGB6 ITGB8 KNG1 LACRT LNX2 PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 SNTG1 TGFB1 TGFB2 TNFRSF11B UBQLN2 VEGFA	5 interacting genes: CMTM7 CREB3 S100B TMED8 VTN
Entrez ID		7448	84830
HPRD ID		01902	12836
Ensembl ID		ENSG00000109072	ENSG00000111863
Uniprot IDs		D9ZGG2 P04004	Q96IZ2
PDB IDs		1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2 4K24 6O5E
Enriched GO Terms of Interacting Partners?
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