Description |
VRK serine/threonine kinase 2 |
mitogen-activated protein kinase kinase kinase 7 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Amyotrophic lateral sclerosis (sporadic) ( 24529757)
- Asthma ( 31959851 29273806)
- Asthma (adult onset) ( 31036433)
- Asthma (childhood onset) ( 31036433)
- Bone mineral density (hip) ( 30172743)
- Celiac disease ( 20190752)
- Graves' disease ( 21841780)
- Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
- Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
- Severity of nausea and vomiting of pregnancy ( 29563502)
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Interacting Genes |
18 interacting genes:
AQP6
CCT2
CCT4
CDC42
DTNBP1
GJA5
LNX1
MAP2K7
MAP3K7
MAPK8IP1
MAPK8IP2
MMGT1
RBX1
TBXA2R
TCP1
TMEM14B
TMEM205
TMEM88
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67 interacting genes:
AKTIP
BBS10
BCL10
CARD11
CHUK
COPS5
CYLD
EIF2AK2
ELP1
EZH2
FOS
GPR25
HGS
HIPK2
IKBKB
IKBKG
IL17RD
IRAK1
MAP2K4
MAP2K6
MAP3K14
MAP3K3
MAP3K5
MAP4K1
MAP4K4
MAPK14
MAPK6
MAPK8
MAPK8IP1
MAVS
MUL1
NAIP
NDUFS6
NFKBIA
NOD2
NRIP1
PEBP1
PELI3
PINK1
PPM1B
PPM1L
PPP2R1A
PPP5C
PRKAB1
RBX1
RELA
RNF19A
ROR2
SMAD3
SMAD6
SMAD7
STAT3
STRADB
TAB1
TAB2
TAB3
TGFBR1
TNFRSF11A
TRAF3
TRAF3IP2
TRAF6
UBASH3A
UBC
VRK2
XIAP
ZNF593
ZNF746
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Entrez ID |
7444 |
6885 |
HPRD ID |
03702 |
04011 |
Ensembl ID |
ENSG00000028116
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ENSG00000135341
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Uniprot IDs |
A8K9L2
Q86Y07
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O43318
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PDB IDs |
2V62
5UU1
6NCG
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2EVA
2YIY
4GS6
4L3P
4L52
4L53
4O91
5E7R
5GJD
5GJF
5GJG
5J7S
5J8I
5J9L
5JGA
5JGB
5JGD
5JH6
5JK3
5V5N
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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