VPS33B and UVRAG

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VPS33B	UVRAG
Description		VPS33B late endosome and lysosome associated	UV radiation resistance associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Golgi Apparatus Clathrin-coated Vesicle HOPS Complex Platelet Alpha Granule Early Endosome Membrane Late Endosome Membrane CORVET Complex Perinuclear Region Of Cytoplasm Recycling Endosome	Lytic Vacuole Autophagosome Membrane Chromosome, Centromeric Region Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Centrosome Midbody Phagocytic Vesicle DNA-dependent Protein Kinase Complex
	Molecular Function	Protein Binding Protein-containing Complex Binding	SNARE Binding Protein Binding SH3 Domain Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome Organization Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Peptidyl-lysine Hydroxylation Melanosome Localization Lysosome Localization Collagen Metabolic Process Membrane Fusion Platelet Alpha Granule Organization Autophagosome Maturation	DNA Repair Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Autophagy Spindle Organization Chromosome Segregation Centrosome Cycle Regulation Of Cytokinesis Receptor Catabolic Process SNARE Complex Assembly Viral Entry Into Host Cell Maintenance Of Golgi Location Regulation Of Protein Serine/threonine Kinase Activity Multivesicular Body Sorting Pathway Autophagosome Maturation Double-strand Break Repair Via Classical Nonhomologous End Joining Positive Regulation Of Autophagosome Maturation
Pathways		Prevention of phagosomal-lysosomal fusion	Macroautophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases		Arthrogryposis, renal dysfunction, and cholestasis; ARC syndrome
GWAS		Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Feeling hurt ( 29500382) Hypertension ( 30226566) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566) Red cell distribution width ( 32888494)	Asthma ( 31619474) HDL cholesterol ( 30275531) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		6 interacting genes: APP MAP3K20 MAPK8IP2 TNIP1 UVRAG VIPAS39	7 interacting genes: CSNK1A1 MTOR VPS11 VPS16 VPS18 VPS33B ZRANB1
Entrez ID		26276	7405
HPRD ID		10541	03929
Ensembl ID		ENSG00000184056	ENSG00000198382
Uniprot IDs		A0A0S2Z577 B7Z1N4 F5H008 Q9H267	Q9P2Y5
PDB IDs
Enriched GO Terms of Interacting Partners?
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