UNG and DAO

Data Source:
BioGRID (pull down)

		UNG	DAO
Description		uracil DNA glycosylase	D-amino acid oxidase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Cytoplasm Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol
	Molecular Function	Damaged DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Ribosomal Small Subunit Binding	D-amino-acid Oxidase Activity Protein Binding Identical Protein Binding FAD Binding
	Biological Process	DNA Repair Base-excision Repair Viral Process Somatic Hypermutation Of Immunoglobulin Genes Negative Regulation Of Apoptotic Process Depyrimidination Isotype Switching Base-excision Repair, AP Site Formation Via Deaminated Base Removal	Proline Catabolic Process Protein Targeting To Peroxisome D-amino Acid Catabolic Process Cellular Nitrogen Compound Metabolic Process D-serine Catabolic Process Dopamine Biosynthetic Process D-alanine Catabolic Process D-serine Metabolic Process
Pathways			Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs		4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE 3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid	3,4-Dihydro-2h-Pyrrolium-5-Carboxylate Imino-Tryptophan Flavin adenine dinucleotide D-Tryptophan Flavin-adenine dinucleotide-N5-isobutyl ketone Benzoic acid Anthranilic acid (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID
Diseases		Hyper IgM syndromes, autosomal recessive type, including the following three diseases: Activation-induced cytidine deaminase (AICD) defect; Uracil nucleotide glycoside glycosylase (UNG) defect; Immunodeficiency with hyper-IgM type 3
GWAS		Feeling miserable ( 29500382) Feeling worry ( 29500382) Neurociticism ( 29500382) Worry too long after an embarrassing experience ( 29500382)	Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
Interacting Genes		5 interacting genes: APP CAPN11 PCNA RPA2 SEZ6L2	5 interacting genes: AOC1 DAOA EP300 PEX5 PRKAB2
Entrez ID		7374	1610
HPRD ID		01881	15917
Ensembl ID		ENSG00000076248	ENSG00000110887
Uniprot IDs		E5KTA5 E5KTA6 P13051	A0A024RBI1 P14920
PDB IDs		1AKZ 1DPU 1EMH 1EMJ 1Q3F 1SSP 1UGH 1YUO 2HXM 2OXM 2OYT 2SSP 3FCF 3FCI 3FCK 3FCL 3TKB 4SKN 5AYR 5JK7	2DU8 2E48 2E49 2E4A 2E82 2GNZ 3CUK 3G3E 3W4I 3W4J 3W4K 3ZNN 3ZNO 3ZNP 3ZNQ 4QFC 4QFD 5ZJ9 5ZJA 6KBP
Enriched GO Terms of Interacting Partners?
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