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UBE2V1 and UBOX5
Data Source:
BioGRID
(two hybrid)
UBE2V1
UBOX5
Description
ubiquitin conjugating enzyme E2 V1
U-box domain containing 5
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Ubiquitin Conjugating Enzyme Complex
Protein-containing Complex
UBC13-UEV1A Complex
Extracellular Exosome
Nucleus
Nucleoplasm
Focal Adhesion
Nuclear Body
Molecular Function
Protein Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-ubiquitin Ligase Activity
Metal Ion Binding
Biological Process
Activation Of MAPK Activity
Protein Polyubiquitination
Regulation Of DNA Repair
Postreplication Repair
Regulation Of Transcription, DNA-templated
JNK Cascade
Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of NF-kappaB Transcription Factor Activity
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Interleukin-1-mediated Signaling Pathway
Protein K63-linked Ubiquitination
Protein Polyubiquitination
Pathways
NOD1/2 Signaling Pathway
TICAM1, RIP1-mediated IKK complex recruitment
Downstream TCR signaling
FCERI mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
CLEC7A (Dectin-1) signaling
Interleukin-1 signaling
IRAK1 recruits IKK complex
IKK complex recruitment mediated by RIP1
Aggrephagy
Aggrephagy
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
Antigen processing: Ubiquitination & Proteasome degradation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Household income (
31844048
)
Household income (MTAG) (
31844048
)
Night sleep phenotypes (
27126917
)
Interacting Genes
47 interacting genes:
ARIH2
BIRC2
BIRC3
BIRC8
CTAG1A
CTAG1B
DAZAP2
DTX3
DZIP3
FAM168A
KITLG
MAP3K1
MID1
MKRN3
PELI1
PELI3
PRKN
PSMD14
RC3H1
RC3H2
RNF10
RNF111
RNF14
RNF144A
RNF185
RNF2
RNF5
SHISA4
SMURF1
STUB1
SUMO4
TRAF2
TRAF3IP2
TRAF6
TRIM25
TRIM32
TRIM39
TRIM5
TRIM8
UBC
UBE2N
UBOX5
UBQLN1
UBQLN2
XBP1
XIAP
ZNRF1
19 interacting genes:
MLH1
NEDD4
TRAF6
TRAIP
TRIM23
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2K
UBE2L3
UBE2V1
UBE2W
USP2
VCP
Entrez ID
7335
22888
HPRD ID
04294
15605
Ensembl ID
ENSG00000244687
ENSG00000185019
Uniprot IDs
G3V2F7
Q13404
O94941
PDB IDs
2A4D
2C2V
2HLW
6D6I
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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