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UBE2D2 and FBXO7
Data Source:
BioGRID
(pull down)
UBE2D2
FBXO7
Description
ubiquitin conjugating enzyme E2 D2
F-box protein 7
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytosol
Protein-containing Complex
Extracellular Exosome
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
SCF Ubiquitin Ligase Complex
Protein-containing Complex
Glial Cytoplasmic Inclusion
Classical Lewy Body
Lewy Neurite
Lewy Body Core
Lewy Body Corona
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Binding
Protein Heterodimerization Activity
Ubiquitin Ligase-substrate Adaptor Activity
Biological Process
Protein Polyubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Protein Targeting To Peroxisome
Protein Ubiquitination
TRIF-dependent Toll-like Receptor Signaling Pathway
Protein Autoubiquitination
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Autophagy Of Mitochondrion
Ubiquitin-dependent Protein Catabolic Process
Protein Targeting To Mitochondrion
Regulation Of Neuron Projection Development
Protein Ubiquitination
Regulation Of Protein Stability
Regulation Of Locomotion
Post-translational Protein Modification
Negative Regulation Of Lymphocyte Differentiation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Oxidative Stress-induced Neuron Death
Positive Regulation Of Autophagy Of Mitochondrion
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
TICAM1, RIP1-mediated IKK complex recruitment
Downstream TCR signaling
FCERI mediated NF-kB activation
CLEC7A (Dectin-1) signaling
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
E3 ubiquitin ligases ubiquitinate target proteins
Neddylation
Peroxisomal protein import
Negative regulators of DDX58/IFIH1 signaling
IKK complex recruitment mediated by RIP1
Antigen processing: Ubiquitination & Proteasome degradation
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
(R,R)-2,3-Butanediol
Diseases
Parkinson's disease (PD)
GWAS
Alzheimer's disease (late onset) (
30820047
)
Body mass index (
26426971
)
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Leukocyte telomere length (
32109421
)
Blood protein levels (
29875488
)
Mean corpuscular hemoglobin (
29403010
32888494
27863252
)
Mean corpuscular volume (
29403010
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
27863252
)
Red blood cell traits (
23222517
)
Red cell distribution width (
32888494
27863252
)
Refractive error (
32231278
)
Interacting Genes
252 interacting genes:
AMFR
ANAPC11
ANAPC2
AREL1
ARIH2
ARRDC3
BARD1
BFAR
BIRC2
BIRC3
BIRC7
BIRC8
BMI1
BRAP
BRCA1
BTRC
CADPS2
CBL
CBLB
CBLC
CCNB1
CDKN1B
CHFR
CNOT4
COP1
CUEDC1
CUL3
CYLD
DCAF1
DDX58
DLST
DTX1
DTX2
DTX3
DTX3L
DZIP3
EPS15
F12
FBXL17
FBXL3
FBXO2
FBXO4
FBXO7
FBXW2
FOXO1
G0S2
H3C1
H4C1
HACE1
HECTD1
HECTD3
HECTD4
HECW1
HECW2
HERC1
HERC2
HERC4
HERC5
HUWE1
ILF3
ITCH
KAT2B
KCMF1
LNX1
LNX2
LRSAM1
LTN1
MAEA
MAP3K1
MAPT
MARCHF3
MARCHF5
MARCHF6
MARCHF7
MDM2
MDM4
MEX3A
MEX3C
MGRN1
MIB1
MIB2
MID1
MID2
MKRN3
MUL1
MYCBP2
MYLIP
NAT10
NBR1
NEDD4
NEDD4L
NFKBIA
NPR1
NSMCE1
OTUB1
PDZRN3
PELI1
PER2
PHF7
PHRF1
PJA1
PJA2
POLL
POLM
PRKN
QSOX1
RAD18
RAF1
RAG1
RBCK1
RBX1
RC3H1
RC3H2
RCHY1
RELA
RFFL
RFWD3
RING1
RLIM
RMND5A
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF122
RNF123
RNF125
RNF126
RNF13
RNF130
RNF135
RNF138
RNF14
RNF146
RNF150
RNF151
RNF166
RNF167
RNF168
RNF170
RNF181
RNF185
RNF186
RNF19A
RNF19B
RNF2
RNF20
RNF213
RNF216
RNF220
RNF224
RNF25
RNF26
RNF31
RNF34
RNF38
RNF4
RNF40
RNF43
RNF5
RNF7
RNF8
RSPRY1
RTF2
SIAH1
SIAH2
SMURF1
SMURF2
SNCA
SOCS6
SPOP
SQSTM1
STAM2
STK11
STUB1
SYVN1
TOPORS
TRAF2
TRAF6
TRAF7
TRAIP
TRIM10
TRIM13
TRIM17
TRIM2
TRIM21
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM3
TRIM31
TRIM32
TRIM33
TRIM35
TRIM36
TRIM37
TRIM38
TRIM39
TRIM41
TRIM43
TRIM45
TRIM46
TRIM47
TRIM5
TRIM50
TRIM54
TRIM55
TRIM62
TRIM63
TRIM65
TRIM7
TRIM8
TRIP12
TTC3
UBA1
UBA3
UBA5
UBA6
UBASH3B
UBB
UBC
UBD
UBE3A
UBE3C
UBE4A
UBE4B
UBOX5
UBR1
UBR2
UBR3
UBR4
UBR5
UBTD1
UFM1
UHRF2
UVSSA
VHL
VPS11
VPS18
WRN
WSB1
WWP1
WWP2
XIAP
ZNRF1
ZNRF2
ZNRF4
345 interacting genes:
AATF
ABCF3
ABL1
ACOT8
ACSL5
ACSM3
ACTC1
ACVR1
ACVR2B
AK8
AKAP14
AKIRIN2
AKT3
ALKBH3
AMOTL2
ANGPTL7
ANKRD36BP1
ANP32E
APEX1
APOBEC3C
APOBEC4
ASPH
ASPHD1
ATAT1
ATF5
ATP5F1C
BAG3
BCKDK
BIRC2
BLK
BUB1
BUB1B
C11orf16
C15orf48
C1orf105
C1orf115
C22orf31
C2orf88
CACYBP
CAMK1
CAPN5
CASQ2
CCBE1
CCDC186
CCDC60
CCDC88C
CCNE2
CDC34
CDK10
CDK14
CENPJ
CEP112
CFAP300
CHCHD2
CHCHD6
CHMP2B
CHMP3
CILK1
CIRBP
CKAP2
CLHC1
CLIP3
CMTR2
CNOT7
COLEC12
CPEB4
CSNK1E
CXCL12
CXCL9
DDRGK1
DDX10
DHRS2
DHX40
DNAH14
DNAJA3
DNAJB12
DNAJC30
DPY19L2P1
DRAP1
ELF4
EP400P1
EPHA3
EPHB2
EPHB3
EPHB4
ERBB2
ERICH2
FGF10
FGF13
FGFR1
FGFR2
FMOD
FUT8
FYTTD1
GADD45GIP1
GAPDH
GBP2
GEMIN2
GGA2
GLCE
GLIPR2
GLRX2
GMCL2
GNLY
GORAB
GPAM
GPKOW
GRK6
GSK3B
H1-0
H2AZ2
H3-3B
HADH
HMG20A
HMG20B
HMGB2
HMGCS2
HNRNPK
HPF1
IDH2
IFT88
IGKV1-5
IL4
IL7
ILKAP
INKA2
INPP5K
INTS7
IPO9
IRF3
JADE2
KCNAB1
KCTD14
KHDRBS3
KIAA1586
KIF12
KIFC3
KIRREL3-AS3
KLF4
KMO
KPNA5
LETMD1
LGALS3BP
LIMK1
LIMK2
LINC01483
LMNA
LRRC20
LRRC8E
LRRFIP1
MAK
MAP2K6
MAPK10
MAPK9
MAPRE2
MARK2
MARK3
MBD5
MBNL1
MCM2
MCM5
MDK
MED22
MED27
MEF2D
MEST
MIR1-1HG-AS1
MIS18BP1
MITF
MMP13
MMP8
MNDA
MOB3A
MOB3C
MPG
MPP3
MPZL1
MRM3
MRPL27
MRPS14
MTIF3
MTUS1
MYOG
NANS
NDE1
NFIA
NFIC
NKD2
NPHP1
NUDT16L1
NUMB
NVL
ODF2L
OLFML2A
OR14K1
ORC3
OSTF1
PABPC3
PACRG
PAFAH1B1
PAK6
PCBD2
PDCD7
PDE12
PDE4D
PDGFB
PGAP4
PHLDA1
PIEZO1
PIGY
PIM1
PIM2
PINK1
PLEKHA1
PNOC
PNRC2
POLDIP2
POLR2K
PPHLN1
PPP1CB
PPP1R17
PPP1R21
PRAME
PRICKLE2
PRKACB
PRKCA
PRKCB
PRKCG
PRKN
PRMT1
PRRC2B
PUF60
PUSL1
QKI
RBBP6
RBM23
RBM33
RCC1
REEP3
REEP4
RET
RGS1
RGS22
RNF121
RNF20
RORB
RPL14
RPL26
RPL36A
RPL37A
RPL3L
RPL6
RPS15A
RPS18
RPS19BP1
RPS2
RPS6KA3
RPS6KB1
RSL24D1
RWDD4
S100A13
S100A16
S100B
SAMHD1
SCARA5
SDCCAG8
SEC16B
SEC24C
SET
SFR1
SHMT1
SHMT2
SKP1
SLAIN1
SLC25A26
SLC35B3
SLC7A6OS
SMARCD1
SMOC2
SNAP25
SNRPA
SNX33
SPATA4
SPDYA
SPRY2
SRCIN1
SRPK3
SRSF10
SRSF7
SS18L2
STAT6
STYX
TAF9B
TARDBP
TBC1D3P2
TBPL1
TC2N
TCP10L3
TEAD4
TEC
TECR
TECRL
TENT5D
TEX29
TGIF2
THAP7
TLE3
TMED10
TMEM120A
TMEM237
TMOD2
TMPRSS5
TOMM20
TRAPPC12
TRIB3
TRIM44
TSBP1
TSLP
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2J2
UBE2M
UROD
USF1
USH1C
UXS1
UXT
VPS16
VRK3
WDR18
WDR24
XPO1
XRN1
YPEL5
ZBTB44
ZC2HC1C
ZFYVE21
ZKSCAN8
ZMYM5
ZNF462
ZNF574
ZNF684
ZNF688
Entrez ID
7322
25793
HPRD ID
04268
07292
Ensembl ID
ENSG00000131508
ENSG00000100225
Uniprot IDs
P62837
Q9Y3I1
PDB IDs
1UR6
1W4U
2CLW
2ESK
2ESO
2ESP
2ESQ
3A33
3JVZ
3JW0
3L1Y
3TGD
3ZNI
4A49
4A4B
4A4C
4AUQ
4DDG
4DDI
4LDT
4V3K
4V3L
4WZ3
5D0K
5D0M
5D1K
5D1L
5D1M
5EDV
5MNJ
5ULF
5ULH
5ULK
5VZW
5ZBU
6HPR
6SQO
6SQR
6SQS
6TTU
6W7Z
6W9D
4L9C
4L9H
Enriched GO Terms of Interacting Partners
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