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TNFRSF4 and BTG2
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
TNFRSF4
BTG2
Description
TNF receptor superfamily member 4
BTG anti-proliferation factor 2
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Nucleus
Cytoplasm
Cytosol
Extracellular Exosome
Molecular Function
Virus Receptor Activity
Tumor Necrosis Factor-activated Receptor Activity
Protein Binding
Transcription Corepressor Activity
Protein Binding
Biological Process
Positive Regulation Of Immunoglobulin Production
Inflammatory Response
Immune Response
Positive Regulation Of B Cell Proliferation
Tumor Necrosis Factor-mediated Signaling Pathway
T Cell Proliferation
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Negative Regulation Of Transcription By RNA Polymerase II
DNA Repair
Protein Methylation
Cellular Response To DNA Damage Stimulus
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Negative Regulation Of Cell Population Proliferation
Associative Learning
Response To Mechanical Stimulus
Anterior/posterior Pattern Specification
Response To Organic Cyclic Compound
Negative Regulation Of Translation
Dentate Gyrus Development
Central Nervous System Neuron Development
Neuron Projection Development
Skeletal Muscle Cell Differentiation
Response To Peptide Hormone
Negative Regulation Of Neuron Apoptotic Process
Negative Regulation Of Mitotic Cell Cycle
Response To Electrical Stimulus
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Negative Regulation Of Neural Precursor Cell Proliferation
Pathways
TNFs bind their physiological receptors
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Immature fraction of reticulocytes (
32888494
27863252
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
27863252
)
Red cell distribution width (
32888494
27863252
28957414
)
Interacting Genes
10 interacting genes:
NUFIP2
RC3H1
SIVA1
TNFRSF9
TNFSF4
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
11 interacting genes:
CNOT7
CNOT8
HOXB9
HOXC8
PICK1
PRKCA
PRMT1
SKP2
SMAD1
SMAD9
SRA1
Entrez ID
7293
7832
HPRD ID
02636
03357
Ensembl ID
ENSG00000186827
ENSG00000159388
Uniprot IDs
P43489
P78543
PDB IDs
1D0A
2HEV
2HEY
6OGX
6OKM
6OKN
3DJU
3E9V
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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