HIRA and NFU1

		HIRA	NFU1
Description		histone cell cycle regulator	NFU1 iron-sulfur cluster scaffold
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GO Annotations	Cellular Component	HIR Complex Chromatin Nucleus Nucleoplasm PML Body Protein-containing Complex Extracellular Exosome	Nucleus Nucleoplasm Mitochondrion Cytosol
	Molecular Function	RNA Polymerase II Transcription Factor Binding Protein Binding Nucleosome Binding Histone Binding	Iron Ion Binding Protein Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Negative Regulation Of Transcription, DNA-templated	Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		16 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 TRIM55 TRIM63 UBE2I UPF1	23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A
Entrez ID		7290	27247
HPRD ID		02583	12163
Ensembl ID		ENSG00000100084	ENSG00000169599
Uniprot IDs		P54198	Q9UMS0
PDB IDs		2I32 5YJE	2LTM 2M5O
Enriched GO Terms of Interacting Partners?
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