Description |
TSC complex subunit 2 |
MAPK activated protein kinase 2 |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Staurosporine
- 3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
- (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE
- (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one
- (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one
- 2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
- 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
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Diseases |
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GWAS |
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Interacting Genes |
44 interacting genes:
AKT1
AKT2
AKT3
CALM1
CBY2
CCND1
CDKN1B
ESR1
FBXL6
FBXW5
GRB2
GSK3B
LNX1
MAPK1
MAPK3
MAPKAPK2
MDFI
NEK1
PAM
PIN1
PLK2
PPP2CA
PRKAA1
PTK2
PTPN11
RAB5A
RABEP1
RHEB
RPS6KA1
SFN
SMAD2
SMAD3
SUPT6H
TK1
TRIM55
TRIM63
TSC1
UBE3A
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
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42 interacting genes:
AGO2
AKT1
ALOX5
ARPC5
ATF1
BAG2
BCL2L1
BECN1
CDC25B
CEP131
CREB1
DDX5
DES
EEF2K
ETV1
HNRNPA0
HSF1
HSPB1
LIMK1
LSP1
MAP2K6
MAPK14
MAPK3
MDM2
PABPC1
PARN
PHC2
PIAS2
RCSD1
SHC1
SRF
STAT3
TCF3
TH
TRIM28
TRIM29
TSC2
UBE2J1
WASF1
YWHAZ
ZFP36
ZFP36L1
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Entrez ID |
7249 |
9261 |
HPRD ID |
01850 |
11882 |
Ensembl ID |
ENSG00000103197
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ENSG00000162889
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Uniprot IDs |
B3KWH7
H3BMQ0
P49815
Q5HYF7
X5D7Q2
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P49137
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PDB IDs |
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1KWP
1NXK
1NY3
2JBO
2JBP
2OKR
2ONL
2OZA
2P3G
2PZY
3A2C
3FPM
3FYJ
3FYK
3GOK
3KA0
3KC3
3KGA
3M2W
3M42
3R2B
3R2Y
3R30
3WI6
4TYH
6TCA
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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