NR2C2 and NR2C2AP

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		NR2C2	NR2C2AP
Description		nuclear receptor subfamily 2 group C member 2	nuclear receptor 2C2 associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm	Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Spermatogenesis Nervous System Development Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development	Transcription Initiation From RNA Polymerase II Promoter
Pathways		Nuclear Receptor transcription pathway	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756)
Interacting Genes		23 interacting genes: AR CD2AP CDC37 CHUK ESR1 FKBP5 HDAC4 HNF4A HSP90AA1 HSP90AB1 IKBKB ITSN2 JAZF1 KDM1A NR2C1 NR2C2AP PEBP1 RAC1 RXRB TAB1 TAB2 TRAF2 TRIM55	7 interacting genes: DDIT4L NR2C2 REL SLC16A3 TCF4 TEPSIN VPS52
Entrez ID		7182	126382
HPRD ID		03253	16376
Ensembl ID		ENSG00000177463	ENSG00000184162
Uniprot IDs		F2YGU2 P49116	Q86WQ0
PDB IDs		3P0U
Enriched GO Terms of Interacting Partners?
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