TPD52 and ANXA6

Data Source:
HPRD (in vivo)

		TPD52	ANXA6
Description		tumor protein D52	annexin A6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Cytoplasm Mitochondrion Lysosomal Membrane Focal Adhesion Membrane Late Endosome Membrane Melanosome Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity	Phosphatidylserine Binding Calcium Channel Activity Calcium Ion Binding Protein Binding GTP Binding Calcium-dependent Phospholipid Binding Lipid Binding Ligand-gated Ion Channel Activity Cholesterol Binding Chondroitin Sulfate Binding Identical Protein Binding Calcium-dependent Protein Binding Actin Filament Binding
	Biological Process	Anatomical Structure Morphogenesis B Cell Differentiation Secretion	Neural Crest Cell Migration Plasma Membrane Repair Growth Plate Cartilage Chondrocyte Differentiation Regulation Of Muscle Contraction Ion Transmembrane Transport Negative Regulation Of Sequestering Of Calcium Ion Mitochondrial Calcium Ion Homeostasis Calcium Ion Transmembrane Transport Apoptotic Signaling Pathway
Pathways		Golgi Associated Vesicle Biogenesis	Smooth Muscle Contraction
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 31959851 27182965 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Inflammatory skin disease ( 25574825) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Psoriasis ( 25903422 25574825) Psoriatic arthritis ( 26626624)
Interacting Genes		14 interacting genes: ANXA6 AR MAL2 SENP2 SH3GLB1 SOCS2 SPG21 SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA	16 interacting genes: A2M CDC73 CR2 ERBB2 IL16 LINC01554 LMNA MLH1 MTNR1B RASA1 RHOU S100A1 S100B SMURF1 SNCA TPD52
Entrez ID		7163	309
HPRD ID		04963	00231
Ensembl ID		ENSG00000076554	ENSG00000197043
Uniprot IDs		P55327	A0A0S2Z2Z6 P08133
PDB IDs			1M9I
Enriched GO Terms of Interacting Partners?
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