TNR and SIGLEC1

Data Source:
HPRD (in vitro)

		TNR	SIGLEC1
Description		tenascin R	sialic acid binding Ig like lectin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Membrane Raft Collagen-containing Extracellular Matrix Perineuronal Net Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Extracellular Region Early Endosome Late Endosome Plasma Membrane Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding	Carbohydrate Binding Virion Binding
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Axon Guidance Associative Learning Telencephalon Cell Migration Negative Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Locomotory Exploration Behavior Negative Regulation Of Axon Extension Involved In Regeneration Negative Regulation Of Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Transmission Of Nerve Impulse Long-term Synaptic Potentiation	Inflammatory Response Cell-matrix Adhesion Clathrin-dependent Endocytosis Of Virus By Host Cell Cell-cell Adhesion
Pathways		ECM proteoglycans	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Beta-D-Glucose N-acetyl-alpha-neuraminic acid
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Attention deficit hyperactivity disorder ( 30563984) Body mass index ( 26426971) Corneal astigmatism ( 29422769) Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644) Liver fibrosis in non-alcoholic fatty acid liver disease ( 31311600) Telomere length ( 30185882) Tonometry ( 17903302)	Blood protein levels ( 29875488) IgM levels ( 28628107) Night sleep phenotypes ( 27126917) Reticulocyte fraction of red cells ( 32888494) Visceral fat ( 30942860)
Interacting Genes		16 interacting genes: ACAN BCAN CCDC146 CNTN1 LGALS14 MAGEB4 NCAN NCK2 NFASC NTAQ1 POLR3C PSMA1 PTPRZ1 SIGLEC1 TRIM54 VCAN	3 interacting genes: MUC1 SPN TNR
Entrez ID		7143	6614
HPRD ID		03589	02854
Ensembl ID		ENSG00000116147	ENSG00000088827
Uniprot IDs		A1L306 Q92752	Q9BZZ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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