SIGLEC1 and TNR

Data Source:
HPRD (in vitro)

		SIGLEC1	TNR
Description		sialic acid binding Ig like lectin 1	tenascin R
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Early Endosome Late Endosome Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Cell Surface Membrane Raft Collagen-containing Extracellular Matrix Perineuronal Net Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	Carbohydrate Binding Virion Binding	Signaling Receptor Binding
	Biological Process	Inflammatory Response Cell-matrix Adhesion Clathrin-dependent Endocytosis Of Virus By Host Cell Cell-cell Adhesion	Cell Adhesion Neuron Cell-cell Adhesion Axon Guidance Associative Learning Telencephalon Cell Migration Negative Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Locomotory Exploration Behavior Negative Regulation Of Axon Extension Involved In Regeneration Negative Regulation Of Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Transmission Of Nerve Impulse Long-term Synaptic Potentiation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	ECM proteoglycans
Drugs		Beta-D-Glucose N-acetyl-alpha-neuraminic acid
Diseases
GWAS		Blood protein levels ( 29875488) IgM levels ( 28628107) Night sleep phenotypes ( 27126917) Reticulocyte fraction of red cells ( 32888494) Visceral fat ( 30942860)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Attention deficit hyperactivity disorder ( 30563984) Body mass index ( 26426971) Corneal astigmatism ( 29422769) Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644) Liver fibrosis in non-alcoholic fatty acid liver disease ( 31311600) Telomere length ( 30185882) Tonometry ( 17903302)
Interacting Genes		3 interacting genes: MUC1 SPN TNR	16 interacting genes: ACAN BCAN CCDC146 CNTN1 LGALS14 MAGEB4 NCAN NCK2 NFASC NTAQ1 POLR3C PSMA1 PTPRZ1 SIGLEC1 TRIM54 VCAN
Entrez ID		6614	7143
HPRD ID		02854	03589
Ensembl ID		ENSG00000088827	ENSG00000116147
Uniprot IDs		Q9BZZ2	A1L306 Q92752
PDB IDs
Enriched GO Terms of Interacting Partners?
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