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TNFRSF1B and CSNK1A1L
Data Source:
BioGRID
(enzymatic study)
TNFRSF1B
CSNK1A1L
Description
TNF receptor superfamily member 1B
casein kinase 1 alpha 1 like
Image
No pdb structure
GO Annotations
Cellular Component
Tumor Necrosis Factor Receptor Superfamily Complex
Extracellular Region
Nucleus
Plasma Membrane
Membrane
Integral Component Of Membrane
Specific Granule Membrane
Neuronal Cell Body
Varicosity
Membrane Raft
Perinuclear Region Of Cytoplasm
Nucleus
Cytoplasm
Cytosol
Molecular Function
Tumor Necrosis Factor-activated Receptor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Tumor Necrosis Factor Binding
Protein Serine/threonine Kinase Activity
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Regulation Of Cytokine Production Involved In Immune Response
Regulation Of T Cell Cytokine Production
Aortic Valve Development
Pulmonary Valve Development
Negative Regulation Of Extracellular Matrix Constituent Secretion
Inflammatory Response
Aging
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Cardiac Muscle Hypertrophy
Cytokine-mediated Signaling Pathway
Regulation Of Myelination
Positive Regulation Of Myelination
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of T Cell Proliferation
Neutrophil Degranulation
Positive Regulation Of Oligodendrocyte Differentiation
RNA Destabilization
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Negative Regulation Of Cell Death
Cellular Response To Lipopolysaccharide
Cellular Response To Growth Factor Stimulus
Extrinsic Apoptotic Signaling Pathway
Regulation Of Neuroinflammatory Response
Negative Regulation Of Neuroinflammatory Response
Glial Cell-neuron Signaling
Negative Regulation Of Neuron Death
Positive Regulation Of Apoptotic Process Involved In Morphogenesis
Regulation Of RNA Biosynthetic Process
Wnt Signaling Pathway
Peptidyl-serine Phosphorylation
Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
TNFR2 non-canonical NF-kB pathway
TNFs bind their physiological receptors
Interleukin-10 signaling
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
Drugs
Tasonermin
Diseases
Graft-versus-host disease
GWAS
Asthma (
31959851
)
Blood protein levels (
30072576
29875488
)
Blood protein levels in cardiovascular risk (
28369058
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Tuberculosis (
29036319
)
Urate levels (BMI interaction) (
25811787
)
Adiponectin levels in pregnancy (
28317342
)
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Palmitoleic acid (16:1n-7) levels (
23362303
)
Interacting Genes
21 interacting genes:
ADAM17
BMX
CAV1
CD14
CSNK1A1
CSNK1A1L
FANCD2
HIVEP3
KRT18
LTA
PKN1
STAT1
TDP2
TNF
TRAF1
TRAF2
TRAF3
TRAIP
TRIM37
UBQLN1
ZNF420
5 interacting genes:
CEACAM3
CEBPE
JAM2
TNFRSF1A
TNFRSF1B
Entrez ID
7133
122011
HPRD ID
01862
13095
Ensembl ID
ENSG00000028137
ENSG00000180138
Uniprot IDs
P20333
Q8N752
PDB IDs
1CA9
3ALQ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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