CSNK1A1L and TNFRSF1B

Data Source:
BioGRID (enzymatic study)

		CSNK1A1L	TNFRSF1B
Description		casein kinase 1 alpha 1 like	TNF receptor superfamily member 1B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Tumor Necrosis Factor Receptor Superfamily Complex Extracellular Region Nucleus Plasma Membrane Membrane Integral Component Of Membrane Specific Granule Membrane Neuronal Cell Body Varicosity Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Tumor Necrosis Factor-activated Receptor Activity Protein Binding Ubiquitin Protein Ligase Binding Tumor Necrosis Factor Binding
	Biological Process	Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Canonical Wnt Signaling Pathway	Regulation Of Cytokine Production Involved In Immune Response Regulation Of T Cell Cytokine Production Aortic Valve Development Pulmonary Valve Development Negative Regulation Of Extracellular Matrix Constituent Secretion Inflammatory Response Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Cardiac Muscle Hypertrophy Cytokine-mediated Signaling Pathway Regulation Of Myelination Positive Regulation Of Myelination Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of T Cell Proliferation Neutrophil Degranulation Positive Regulation Of Oligodendrocyte Differentiation RNA Destabilization Positive Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of Cell Death Cellular Response To Lipopolysaccharide Cellular Response To Growth Factor Stimulus Extrinsic Apoptotic Signaling Pathway Regulation Of Neuroinflammatory Response Negative Regulation Of Neuroinflammatory Response Glial Cell-neuron Signaling Negative Regulation Of Neuron Death Positive Regulation Of Apoptotic Process Involved In Morphogenesis Regulation Of RNA Biosynthetic Process
Pathways			TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation
Drugs			Tasonermin
Diseases			Graft-versus-host disease
GWAS		Adiponectin levels in pregnancy ( 28317342) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Palmitoleic acid (16:1n-7) levels ( 23362303)	Asthma ( 31959851) Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Tuberculosis ( 29036319) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		5 interacting genes: CEACAM3 CEBPE JAM2 TNFRSF1A TNFRSF1B	21 interacting genes: ADAM17 BMX CAV1 CD14 CSNK1A1 CSNK1A1L FANCD2 HIVEP3 KRT18 LTA PKN1 STAT1 TDP2 TNF TRAF1 TRAF2 TRAF3 TRAIP TRIM37 UBQLN1 ZNF420
Entrez ID		122011	7133
HPRD ID		13095	01862
Ensembl ID		ENSG00000180138	ENSG00000028137
Uniprot IDs		Q8N752	P20333
PDB IDs			1CA9 3ALQ
Enriched GO Terms of Interacting Partners?
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