TSPAN4 and PHLDA1

Data Source:
BioGRID (two hybrid)

		TSPAN4	PHLDA1
Description		tetraspanin 4	pleckstrin homology like domain family A member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Vesicle	Nucleus Nucleoplasm Nucleolus Cytosol Cytoplasmic Vesicle
	Molecular Function	Antigen Binding Integrin Binding Protein Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Protein-containing Complex Assembly	G2/M Transition Of Mitotic Cell Cycle Apoptotic Process Positive Regulation Of Apoptotic Process FasL Biosynthetic Process
Pathways			Interaction between PHLDA1 and AURKA
Drugs
Diseases
GWAS		Falling risk ( 32999390)	Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Atrial fibrillation ( 30061737 29892015) Blood trace element (Cu levels) ( 23720494) Blood urea nitrogen levels ( 31152163 29403010) Creatinine levels ( 29403010) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate ( 29403010) Glomerular filtration rate (creatinine) ( 26831199) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3	41 interacting genes: APP CDPF1 CYSRT1 EIF3D F2RL1 FBXO7 HSPA4 HSPA4L KPRP KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP5-1 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LGALS13 MDFI NBPF19 NOTCH2NLA PABPC4 PLSCR1 RPL14 TRAF4 TRIM42 TSPAN4
Entrez ID		7106	22822
HPRD ID		04033	05625
Ensembl ID		ENSG00000214063	ENSG00000139289
Uniprot IDs		A0A024RCE1 A8MVV6 O14817	Q8WV24
PDB IDs
Enriched GO Terms of Interacting Partners?
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