TSPAN7 and RPGR

Data Source:
HPRD (in vivo)

		TSPAN7	RPGR
Description		tetraspanin 7	retinitis pigmentosa GTPase regulator
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	Protein Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Viral Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly
Pathways		Cell surface interactions at the vascular wall Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases		Non-syndromic X-linked mental retardation	Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)
GWAS		White blood cell count ( 32888494)
Interacting Genes		22 interacting genes: ADRB2 BBS1 BUD31 CACNA1A CCR2 CCR9 CHRM2 CHRM4 CREB3 DRD2 FAM209A FYTTD1 GNRHR GPR152 GPR35 HTR4 LHFPL5 LMNA LTB4R2 MEOX2 OXTR SMO	14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE
Entrez ID		7102	6103
HPRD ID		02107	02425
Ensembl ID		ENSG00000156298	ENSG00000156313
Uniprot IDs		P41732	Q92834
PDB IDs			4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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