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TSPAN7 and CHRM4
Data Source:
BioGRID
(two hybrid)
TSPAN7
CHRM4
Description
tetraspanin 7
cholinergic receptor muscarinic 4
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Dendrite
Synapse
Postsynaptic Membrane
Molecular Function
Protein Binding
G Protein-coupled Serotonin Receptor Activity
Protein Binding
G Protein-coupled Acetylcholine Receptor Activity
Neurotransmitter Receptor Activity
Biological Process
Viral Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Chemical Synaptic Transmission
Regulation Of Locomotion
G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways
Cell surface interactions at the vascular wall
Trafficking of GluR2-containing AMPA receptors
Muscarinic acetylcholine receptors
G alpha (i) signalling events
Drugs
Ziprasidone
Amitriptyline
Olanzapine
Metixene
Terfenadine
Clozapine
Doxylamine
Trihexyphenidyl
Procyclidine
Loxapine
Carbamoylcholine
Hyoscyamine
Meperidine
Imipramine
Darifenacin
Nortriptyline
Amoxapine
Cinnarizine
Atropine
Nicardipine
Paroxetine
Homatropine methylbromide
Trimipramine
Scopolamine
Benzquinamide
Propiomazine
Tropicamide
Brompheniramine
Maprotiline
Methantheline
Bethanechol
Tolterodine
Promethazine
Pilocarpine
Doxepin
Desipramine
Ketamine
Quetiapine
Aripiprazole
Chlorprothixene
Methotrimeprazine
Tiotropium
Solifenacin
Isopropamide
Acetylcholine
ALKS 27
Fesoterodine
Hexocyclium
Aclidinium
Umeclidinium
Trimebutine
Dosulepin
Etoperidone
Homatropine
Thonzylamine
Revefenacin
Propiverine
Rociverine
Aripiprazole lauroxil
Diseases
Non-syndromic X-linked mental retardation
GWAS
White blood cell count (
32888494
)
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Autism spectrum disorder or schizophrenia (
28540026
)
Schizophrenia (
28991256
29483656
)
Interacting Genes
22 interacting genes:
ADRB2
BBS1
BUD31
CACNA1A
CCR2
CCR9
CHRM2
CHRM4
CREB3
DRD2
FAM209A
FYTTD1
GNRHR
GPR152
GPR35
HTR4
LHFPL5
LMNA
LTB4R2
MEOX2
OXTR
SMO
20 interacting genes:
B2M
CBFA2T3
CD59
CD81
EEF1A2
ERGIC3
GPRASP1
GRB2
MCL1
METTL9
MFSD4A
QSOX1
RAB3A
RHBDD2
RTN4
SMIM7
SYN2
TM7SF2
TSPAN7
YIPF3
Entrez ID
7102
1132
HPRD ID
02107
00330
Ensembl ID
ENSG00000156298
ENSG00000180720
Uniprot IDs
P41732
P08173
PDB IDs
5DSG
6D9H
6KP6
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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