TGFB1I1 and DOC2A

Data Source:
BioGRID (affinity chromatography technology)

		TGFB1I1	DOC2A
Description		transforming growth factor beta 1 induced transcript 1	double C2 domain alpha
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL	5 interacting genes: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B
Entrez ID		7041	8448
HPRD ID		03831	05195
Ensembl ID		ENSG00000140682	ENSG00000149927
Uniprot IDs		A0A024QZE7 O43294	Q14183
PDB IDs			4MJJ
Enriched GO Terms of Interacting Partners?
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