TFAP2C and ZFAND4

Data Source:
BioGRID (two hybrid)

		TFAP2C	ZFAND4
Description		transcription factor AP-2 gamma	zinc finger AN1-type containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Male Gonad Development Regulation Of Gene Expression, Epigenetic Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development
Pathways		SUMOylation of transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors TFAP2 (AP-2) family regulates transcription of other transcription factors Activation of the TFAP2 (AP-2) family of transcription factors TFAP2 (AP-2) family regulates transcription of growth factors and their receptors TFAP2 (AP-2) family regulates transcription of cell cycle factors
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Blood urea nitrogen levels ( 31152163) Cerebrospinal P-tau181p levels ( 28247064) Chronic obstructive pulmonary disease (moderate to severe) ( 24621683) Cognitive decline rate in late mild cognitive impairment ( 26252872) Maximum stenosis ( 32469969) Mean degree of stenosis ( 32469969) Ovarian cancer ( 30557369) Refractive error ( 32231278) Sum of stenosis ( 32469969)	Blood protein levels ( 29875488) Mean corpuscular volume ( 29403010)
Interacting Genes		12 interacting genes: CCNG1 CITED1 CITED2 CITED4 ERBB4 GPR22 IKBKB NR1I2 TP53 UBE2I WWOX ZFAND4	1 interacting genes: TFAP2C
Entrez ID		7022	93550
HPRD ID		03361	16494
Ensembl ID		ENSG00000087510	ENSG00000172671
Uniprot IDs		Q92754	A0A024R7V9 A8K8Q5 J3KPC0 Q86WR3 Q86XD8
PDB IDs
Enriched GO Terms of Interacting Partners?
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