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TFAP2C and CITED1
Data Source:
HPRD
(in vitro)
TFAP2C
CITED1
Description
transcription factor AP-2 gamma
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Mitochondrion
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Chromatin Binding
Transcription Coactivator Activity
Protein Binding
Protein C-terminus Binding
Protein Homodimerization Activity
LBD Domain Binding
Co-SMAD Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Cell-cell Signaling
Male Gonad Development
Regulation Of Gene Expression, Epigenetic
Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Anatomical Structure Development
Embryonic Axis Specification
Vasculogenesis
Metanephros Development
Branching Involved In Ureteric Bud Morphogenesis
Placenta Development
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Nucleocytoplasmic Transport
Apoptotic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Brain Development
Positive Regulation Of Gene Expression
Negative Regulation Of Wnt Signaling Pathway
Melanocyte Differentiation
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Lipopolysaccharide
Response To Insulin
Response To Cytokine
Response To Interferon-gamma
Melanin Biosynthetic Process
Regulation Of Apoptotic Process
Pigmentation
Negative Regulation Of Neuron Apoptotic Process
Response To Estrogen
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Response To CAMP
Mesenchymal To Epithelial Transition
SMAD Protein Signal Transduction
Labyrinthine Layer Development
Response To Interleukin-1
Response To Interleukin-2
Response To Interleukin-4
Response To Interleukin-6
Response To Interleukin-9
Response To Interleukin-11
Response To Parathyroid Hormone
Response To Transforming Growth Factor Beta
Positive Regulation Of Mesenchymal Stem Cell Proliferation
Pathways
SUMOylation of transcription factors
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
TFAP2 (AP-2) family regulates transcription of other transcription factors
Activation of the TFAP2 (AP-2) family of transcription factors
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
TFAP2 (AP-2) family regulates transcription of cell cycle factors
Activation of the TFAP2 (AP-2) family of transcription factors
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Blond vs. brown/black hair color (
30531825
)
Blood urea nitrogen levels (
31152163
)
Cerebrospinal P-tau181p levels (
28247064
)
Chronic obstructive pulmonary disease (moderate to severe) (
24621683
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Maximum stenosis (
32469969
)
Mean degree of stenosis (
32469969
)
Ovarian cancer (
30557369
)
Refractive error (
32231278
)
Sum of stenosis (
32469969
)
Chloride levels (
29403010
)
Sodium levels (
29403010
)
Interacting Genes
12 interacting genes:
CCNG1
CITED1
CITED2
CITED4
ERBB4
GPR22
IKBKB
NR1I2
TP53
UBE2I
WWOX
ZFAND4
8 interacting genes:
CREBBP
EP300
ESR1
HSPA8
LNX1
SMAD4
TFAP2B
TFAP2C
Entrez ID
7022
4435
HPRD ID
03361
02146
Ensembl ID
ENSG00000087510
ENSG00000125931
Uniprot IDs
Q92754
Q99966
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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