TFAP2A and NFKB1

  • Data Source:
  • BioGRID (two hybrid)

TFAP2A

NFKB1

Description transcription factor AP-2 alpha nuclear factor kappa B subunit 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Breast cancer in BRCA2 mutation carriers ( 23544012)
  • Glucose homeostasis traits ( 25524916)
  • Iron status biomarkers (ferritin levels) ( 28334935)
  • Metabolite levels ( 23823483)
  • Ovarian cancer ( 30557369)
  • Refractive error ( 32231278)
  • Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
  • Zinc levels ( 26025379)
Interacting Genes 38 interacting genes: APC CASP1 CASP3 CASP6 CITED2 CITED4 CLTC CSNK2A1 CSNK2B CTNNB1 DEK EP300 EPN1 EPN2 EPS15 GSTO2 HIP1 INCA1 KCTD15 LDLRAP1 MAGI1 MKRN3 MYC NFKB1 NPM1 PPARG PRKAA2 PRKD1 RB1 SRA1 SUMO4 SYT1 TP53 UBE2I VEGFA WWP1 WWP2 YBX1 104 interacting genes: ABCC2 APBB2 AR ATF3 BCL3 BRCA1 BTRC CDK9 CEBPB CFLAR CHUK COPB2 COPS5 CTNNB1 DNMT3L E2F1 ECSIT ELF1 ELF3 ESR1 ETS1 FBXW11 FOS G3BP2 GLUL GSK3B HDAC1 HMGA1 HMGA2 HMGB1 HSPA4 IKBKB IKBKG IL2RA IRF1 IRF2 IRF8 IRF9 ITGB3BP KAT5 KLF5 KPNA3 LYL1 MAP3K8 MEN1 MTPN NCOA1 NCOA6 NCOR2 NFKB2 NFKBIA NFKBIB NFKBIE NFKBIZ NFRKB NKRF NOTCH1 NR3C1 NR4A1 PALS2 PARP1 PCBD1 PDCD11 PELP1 PLD3 PML PPARG PPP4C PRKACA PSMD10 REL RELA RELB RGS14 RIPK1 RPS3 RSF1 RXRA SERPINA3 SF1 SIN3A SP1 SPAG9 SPI1 SPPL2A SRF STAT3 STAT6 TAB2 TFAP2A TNFSF11 TNIP1 TNIP2 TP53BP1 TP53BP2 TRIP4 TSC22D3 TXN UBE2D3 UBE2K UNC5CL YWHAQ YY1 ZBTB9
Entrez ID 7020 4790
HPRD ID 00128 01238
Ensembl ID ENSG00000137203 ENSG00000109320
Uniprot IDs P05549 P19838
PDB IDs 1MDI 1MDJ 1MDK 1NFI 1SVC 2DBF 2O61 3GUT
Enriched GO Terms of Interacting Partners?
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