TCP11 and LMBRD1

Data Source:
BioGRID (two hybrid)

		TCP11	LMBRD1
Description		t-complex 11	LMBR1 domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Integral Component Of Membrane Sperm Flagellum Sperm Midpiece	Lysosomal Membrane Vacuolar Membrane Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function		Protein Binding ABC-type Vitamin B12 Transporter Activity Cobalamin Binding
	Biological Process	Signal Transduction Multicellular Organism Development Spermatogenesis Protein Kinase A Signaling Cell Differentiation Regulation Of CAMP-mediated Signaling Regulation Of Sperm Capacitation	Cobalamin Metabolic Process Cobalamin Transport Viral Process Protein Localization To Lysosome Protein Localization To Vacuole
Pathways			Cobalamin (Cbl, vitamin B12) transport and metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Drugs
Diseases			Methylmalonic aciduria (MMA)
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Height ( 28552196 18391951) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 28714469)	Response to statin therapy ( 20339536) Sleep duration ( 25469926)
Interacting Genes		13 interacting genes: AIMP2 APP FANCF GRAPL GSTZ1 IKBKG KRTAP13-3 LMBRD1 MAP2K1 MED28 NPFFR1 VAV2 ZNF688	1 interacting genes: TCP11
Entrez ID		6954	55788
HPRD ID		01749	12877
Ensembl ID		ENSG00000124678	ENSG00000168216
Uniprot IDs		B7ZAT8 Q8WWU5	Q9NUN5
PDB IDs
Enriched GO Terms of Interacting Partners?
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